| MID | Week | Date | Day | Kick-off | Home Team | Away Team | Venue |
|---|---|---|---|---|---|---|---|
| 41 | 5 | 2024-09-21 | Sat | 12:30 | West Ham | Chelsea | London Stadium |
| 42 | 5 | 2024-09-21 | Sat | 15:00 | Liverpool | Bournemouth | Anfield |
| 43 | 5 | 2024-09-21 | Sat | 15:00 | Leicester City | Everton | King Power Stadium |
| 44 | 5 | 2024-09-21 | Sat | 15:00 | Southampton | Ipswich Town | St Mary's Stadium |
| 45 | 5 | 2024-09-21 | Sat | 15:00 | Tottenham | Brentford | Tottenham Hotspur Stadium |
| 46 | 5 | 2024-09-21 | Sat | 15:00 | Fulham | Newcastle Utd | Craven Cottage |
| 47 | 5 | 2024-09-21 | Sat | 15:00 | Aston Villa | Wolves | Villa Park |
| 48 | 5 | 2024-09-21 | Sat | 17:30 | Crystal Palace | Manchester Utd | Selhurst Park |
| 49 | 5 | 2024-09-22 | Sun | 14:00 | Brighton | Nottingham Forest | The American Express Stadium |
| 50 | 5 | 2024-09-22 | Sun | 16:30 | Manchester City | Arsenal | Etihad Stadium |
| For prediction columns, 1: home win, 2: away win, 3: draw | |||||||