| MID | Week | Date | Day | Kick-off | Home Team | Away Team | Venue |
|---|---|---|---|---|---|---|---|
| 261 | 27 | 2025-02-25 | Tue | 19:45 | West Ham | Leicester City | London Stadium |
| 262 | 27 | 2025-02-25 | Tue | 19:45 | Brentford | Everton | Gtech Community Stadium |
| 263 | 27 | 2025-02-25 | Tue | 19:45 | Tottenham | Manchester City | Tottenham Hotspur Stadium |
| 264 | 27 | 2025-02-25 | Tue | 19:45 | Wolves | Fulham | Molineux Stadium |
| 265 | 27 | 2025-02-25 | Tue | 19:45 | Nottingham Forest | Arsenal | The City Ground |
| 266 | 27 | 2025-02-25 | Tue | 19:45 | Brighton | Bournemouth | The American Express Stadium |
| 267 | 27 | 2025-02-25 | Tue | 20:00 | Crystal Palace | Aston Villa | Selhurst Park |
| 268 | 27 | 2025-02-26 | Wed | 19:45 | Chelsea | Southampton | Stamford Bridge |
| 269 | 27 | 2025-02-26 | Wed | 20:00 | Liverpool | Newcastle Utd | Anfield |
| 270 | 27 | 2025-02-26 | Wed | 20:00 | Manchester Utd | Ipswich Town | Old Trafford |
| For prediction columns, 1: home win, 2: away win, 3: draw | |||||||